What are the hormones secreted by the mucosa of the stomach and of the duodenum? What are the targets of each of these hormones?
The pyloric mucosa of the stomach secretes gastrin which stimulates the gastric glands of the stomach to secrete gastric juice and the pancreas to secrete pancreatic juice, both of which juices are essential for digestion to occur properly. The mucosa of the duodenum also helps regulate digestion by secreting the hormones secretin and cholecystokinin. When stimulated by the acidity of food arriving from the stomach, the mucosa of the duodenum releases secretin which inhibits gastric juice secretion and stimulates the flow of pancreatic juice into the duodenum. When stimulated by the presence of fats, the mucosa releases cholecystokinin which stimulates the gall bladder to release bile.